联系方式
邮箱:lrjuan@hit.edu.cn
个人简介
教育经历:
2003.9-2007.7 44118太阳成城集团 计算机科学与技术专业 本科
2007.9-2009.7 44118太阳成城集团 计算机科学与技术专业 硕士
2009.9-2015.3 44118太阳成城集团 计算机科学与技术专业 博士
工作经历:
2015.5-2020.12 44118太阳成城集团44118太阳成城集团 讲师
2020.12-至今 44118太阳成城集团44118太阳成城集团 副教授
Personal Profile
EDUCATION:
B.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2003-2007
M.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2007-2009
Ph.D. Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2009-2015
ACADEMIC APPOINTMENTS:
Lecturer, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2015-2020
Associate Professor, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2020-present
研究方向和领域
生物信息学
Bioinformatics
研究内容
主要研究方向为基因组大数据分析方法与软件,包括三方面内容:
1. 基因组学机器学习,研究机器学习算法在基因组学问题上的应用与改进;
2. 基因组注释与可视化,研究对容量庞大、格式多样、关系复杂的基因组大数据进行注释及可视化方法与软件;
3. 多组学数据分析,运用统计、计算方法,分析多组学数据、解决生物学问题。
Research Interests
The major research area is methods and software of genome bigdata analysis, including 3 topics:
1. Machine learning in genomics: Improvement and application of machine learning algorithm for genomics.
2. Genome annotation and visualization: Annotation and visualization methods/software for genome bigdata with mass volume, various formats and complex relationship.
3. Multi-omics data analysis, Analyzing multi-omics data by computational and statistical methods, solving biological problem.
研究成果
代表性论文
1. Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Wang, G., and Wang, Y.* (2020). Evaluating Individual Genome Similarity with a Topic Model. Bioinformatics.(SCI检索)
2. Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Jiang, Q., and Wang, Y.* (2020). PGsim: A Comprehensive and Highly Customizable Personal Genome Simulator. Front Bioeng Biotechnol 8, 28.(SCI检索)
3. Juan, L., Liu, Y., Wang, Y., Teng, M.,Zang, T., and Wang, Y. (2015). Family genome browser: visualizing genomes with pedigree information. Bioinformatics 31, 2262-2268. (SCI检索)
4. Juan, L., Teng, M., Zang, T., Hao, Y.,Wang, Z., Yan, C., Liu, Y., Li, J., Zhang, T., and Wang, Y. (2014). The personal genome browser: visualizing functions of genetic variants. Nucleic Acids Res 42, W192-197. (SCI检索)
5. Juan, L., Wang, G., Radovich, M.,Schneider, B.P., Clare, S.E., Wang, Y., and Liu, Y. (2013). Potential roles of microRNAs in regulating long intergenic noncoding RNAs. BMC Medical Genomics 6 Suppl 1,S7. (SCI检索)
获奖
2019年度黑龙江省科学技术一等奖(排名4)
开设的课程
生物信息学
Bioinformatics
生物数据库及软件应用基础
Foundation of Biological Database and Software
基因组信息学
Genome Informatics